COSA PUR 81 is designed for difficult sustained-release and retard-coating residues. It supports CIP and manual cleaning of pharmaceutical and nutritional supplement equipment and may be combined with COSA FOAM 40 where a foam application is required.
Key features and benefits
- Targeted removal of sustained-release and retard coatings.
- Suitable for Eudragit RL and RS types and other specified coating systems.
- Low-foaming formulation suitable for CIP systems.
- Can be used for manual cleaning and selected foam applications.
- Supported by Ecolab validation and residue-analysis documentation.
Applications
- Typical concentration varies by coating system, with manufacturer guidance ranging from 2% to 10% under the listed procedures.
- Typical operating temperature is 50-85 C after an optional 30-40 C pre-rinse.
- A 50-60 C post-rinse and final rinse with water of minimum drinking-water quality at ambient temperature are specified.
- Cleaning conditions should be selected for the exact coating chemistry and confirmed through cleaning trials.
Technical overview
| Appearance | Clear, colourless to yellow liquid |
| pH | 3.0-4.0 at 1% in deionised water; concentrate pH 4.0-5.0 |
| Foam behaviour | Low-foaming and suitable for CIP systems |
| Water quality | Minimum drinking-water quality |
| Compatible metals | Austenitic CrNi steel, at least DIN 1.4301 / AISI 304, and coated enamel |
| Compatible plastics | PE, PP, PVC and PTFE under the stated application conditions |
Application conditions should be confirmed for the specific equipment, soil and cleaning process. Use in accordance with the current manufacturer sell sheet, Safety Data Sheet and site validation procedures.
Validation and documentation
The Ecolab documentation package includes Certificates of Analysis, analytical method descriptions for residue analysis, ecological assessment, toxicological and limit-setting information, and a Safety Data Sheet.
